Zolpip

Description

Zolpip contains esomeprazole, a proton pump inhibitor that lowers gastric acid by blocking the proton pump in stomach parietal cells. It is commonly used in Pakistan for GERD, peptic ulcers, esophagitis, and to prevent ulcer formation in patients using NSAIDs or those infected with H. pylori.

Primary Uses

• Gastroesophageal Reflux Disease (GERD).

• Acid-induced esophageal inflammation.

• Peptic and duodenal ulcers.

• Ulcer prevention in NSAID users.

• H. pylori-associated gastritis (as part of combination therapy).

How to Use

• Swallow the capsule whole with water.

• Preferably take before meals, ideally in the morning.

• Do not crush or chew.

• Duration depends on indication – follow your doctor’s instructions.

Side Effects

Common reactions:

• Headache · Dizziness.

• Dry mouth.

• GI upset (nausea, diarrhea, abdominal discomfort).

• Skin rash or itching.

Rare but important:

• Vitamin B12 deficiency (long-term).

• Low magnesium.

• Kidney inflammation (if taken chronically).

Warnings & Precautions

• Rule out gastric malignancy before starting prolonged PPI therapy.

• Use with caution in liver or kidney impairment.

• Prolonged use may increase risk of fractures and B12 deficiency.

• Not recommended for long-term self-medication without supervision.

When Not to Use

• Known allergy to esomeprazole or other PPIs.

• Severe liver dysfunction without medical monitoring.

• Concomitant use with rilpivirine (HIV therapy).

FAQs

Doctor’s Overview

Dr. Ayesha Malik (Gastroenterologist):
“Esomeprazole remains a reliable choice for GERD and ulcer protection. It works well when used for the right duration.”

Storage

• Keep at room temperature, away from heat and moisture.

• Store in original strip, out of reach of children.

Disclaimer

This profile is for informational reference based on standard Pakistani prescribing guidelines. It is not a substitute for medical advice. Always consult a registered physician before initiating or discontinuing treatment.