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Cefoperazone Injection

Requires Prescription

• Yes.

Generic Name

• Cefoperazone.

Used For

• Respiratory tract infections.

• Intra-abdominal infections and peritonitis.

• Septicemia (blood infections).

• Skin and soft tissue infections.

• Pelvic inflammatory disease, endometritis, and other female reproductive tract infections.

How It Works

• Cefoperazone is a third-generation cephalosporin antibiotic. It kills bacteria by inhibiting cell wall synthesis, making it effective against a broad range of bacteria, including Pseudomonas.

Dosage

• Administered by a nurse or trained healthcare professional.

• Given as an intravenous (IV) or intramuscular (IM) injection.

• Follow the exact dosage prescribed by your doctor.

In Case of Overdose

• Symptoms: nausea, vomiting, diarrhea, rash, dizziness

• Seek immediate medical attention.

Missed Dose

• Administer the missed dose as soon as possible if still appropriate.

• If it’s near the time of the next dose, skip it.

• Do not double the dose.

How to Use

• Administer via IV or IM as instructed by a healthcare professional.

• Complete the full course, even if symptoms improve early.

When Not to Use

• Allergy to cefoperazone, other cephalosporins, penicillins, or sulbactam.

• Severe liver or kidney impairment without medical supervision.

• In neonates or specific conditions as advised by a doctor.

Side Effects

• Rash, diarrhea, nausea, vomiting.

• Decreased white blood cells or hemoglobin.

• Eosinophilia (high eosinophils).

• Increased liver enzymes.

• Rare: superinfections.

Precautions

• Use caution in patients with colitis or bleeding disorders.

• Dose adjustments may be needed for liver or kidney disease.

• Avoid alcohol during treatment.

• Prolonged use may lead to secondary infections.

Drug Interactions

• May interact with other antibiotics or anticoagulants.

• Inform your doctor about all medications being taken.

Food Interactions

• Can be taken with or without food.

• Ensure proper hydration.

Storage

• Store at room temperature, away from light and moisture.

• Keep out of reach of children.

• Do not reuse or share vials.

• Dispose of unused medication according to pharmacist instructions.

Reviewed by: Dr. Ahmed Khan, Infectious Disease Specialist
Cefoperazone Injection is a broad-spectrum antibiotic effective against serious bacterial infections. Administration should be done only by trained healthcare professionals, with monitoring for liver, kidney, and blood-related side effects.

Disclaimer: For general guidance only. Follow your doctor’s instructions.