Zymacef

Description

Cefotaxime is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections, including cervicitis, gonococcal urethritis, rectal gonorrhea, urinary tract infections, respiratory infections, and skin infections. It is also prescribed as a preventive measure before surgeries to reduce the risk of infection. Cefotaxime works by stopping bacterial growth, helping the body’s immune system fight off infections more effectively.

Uses

• Cervicitis and gonococcal urethritis.

• Rectal gonorrhea.

• Bacterial infections (respiratory, urinary, skin, joint, abdominal, blood).

• Prophylaxis (prevention) of infections in surgical patients.

• Sepsis and meningitis (as per doctor’s advice).

How to Use

• Given as an injection into a vein (IV) or muscle (IM).

• Usually administered by a doctor or trained healthcare professional.

• If prescribed for home use:

  • Learn proper preparation, dilution, and injection techniques.

  • Always check instructions carefully before use.

• Complete the full treatment course, even if symptoms improve early.

• Do not self-medicate without medical supervision.

Expert Advice

• If using a pre-mixed frozen solution, thaw in the fridge or at room temperature. Do not use boiling water or a microwave.

• Once thawed, shake well and check for leakage—discard if the bag leaks.

• Do not refreeze once thawed.

• Take doses at regular intervals for best effect.

• Do not stop treatment early, as this may cause the infection to return.

• Store at room temperature, away from children and pets.

• Do not use beyond the expiration date.

Side Effects

• Pain, redness, or swelling at injection site.

• Nausea, vomiting, or diarrhea.

• Rash or itching.

• Headache or dizziness.

• Rare but serious: allergic reaction (swelling, difficulty breathing), seizures, or severe diarrhea (C. difficile infection).

Warnings & Precautions

• Do not use if allergic to Cefotaxime or other cephalosporins.

• Use cautiously in patients with kidney or liver problems—dose adjustment may be needed.

• Inform your doctor about any history of allergic reactions to penicillin or other antibiotics.

• Pregnant or breastfeeding women should use only if prescribed by a doctor.

• Long-term use may cause secondary infections—monitor under medical guidance.

Interactions

• May interact with diuretics, aminoglycosides, and anticoagulants (risk of kidney issues or bleeding).

• Inform your doctor about all ongoing medications before starting Cefotaxime.

Storage & Disposal

• Store at room temperature, away from sunlight and moisture.

• Do not freeze unless instructed for pre-mixed bags.

• Dispose of unused medicine safely; do not flush into drains.

Doctor’s Review

Dr. Imran Siddiqui, Consultant Infectious Disease Specialist:
“Cefotaxime is a trusted third-generation cephalosporin that’s effective against many serious bacterial infections, including gonorrhea and surgical prophylaxis. It is usually well tolerated, though injection site pain and mild digestive upset are common.”

Disclaimer

This profile is for educational purposes only and does not replace medical advice. Always use Cefotaxime under the supervision of a qualified healthcare professional.