Calfina CR

Description Calfina CR 100mg Tablets contain Tramadol HCl (100mg), an opioid analgesic used to manage moderate to severe pain. It acts on the central nervous system by binding to mu-opioid receptors and inhibiting the reuptake of serotonin and norepinephrine, altering pain perception in the brain and spinal cord. This controlled-release formulation provides up to 24 hours of steady pain relief, making it suitable for chronic conditions like arthritis or post-surgical discomfort in adults.

Ingredients Tramadol HCl 100mg.

Drug Class Opioid Analgesic / Centrally Acting Analgesic.

Dosage Form Controlled-Release Tablet (1 strip = 10 tablets; 1 box = 1 strip).

Uses Calfina CR Tablets are prescribed for:

• Moderate to severe acute or chronic pain (e.g., post-operative, musculoskeletal).
• Pain from osteoarthritis, rheumatoid arthritis, backache, or migraines.
• Neuropathic pain or cancer-related discomfort.
• Prevention of pain in anticipated flare-ups.
• Adjunct in inflammatory conditions with pain.

Doctor’s Review Pain management specialists and orthopedists often turn to Calfina CR for sustained relief in ongoing pain scenarios. As one expert puts it: “Calfina CR is effective for patients needing round-the-clock pain control without frequent dosing. Its extended-release design helps maintain steady levels, but close monitoring is essential to avoid dependency risks.”

Dosage (Follow physician’s instructions — typical guideline)

• Adults: 100mg once daily, swallowed whole with water; may increase to 200mg if needed after 1-2 days.
• Elderly or those with kidney/liver issues: Start at 50-100mg, adjust based on response.
• Maximum: 300mg daily; taper off gradually to prevent withdrawal.
• Not for children under 12 years.

In Case of Overdose Overdose can cause severe respiratory depression, drowsiness leading to coma, seizures, or low blood pressure. Seek emergency help immediately. Symptoms include extreme sleepiness, slow breathing, or muscle weakness. Treatment may involve naloxone for reversal, activated charcoal if recent, and supportive care like oxygen or ventilation. Monitor for serotonin syndrome if combined with other drugs.

Missed Dose Take as soon as remembered if within 8 hours of scheduled time. Skip if closer to the next dose—do not double up, as it risks overdose symptoms like nausea or dizziness. Resume your regular schedule and tell your doctor about frequent misses.

How to Use

• Swallow the tablet whole with plenty of water; do not crush, chew, break, or dissolve to avoid rapid release and overdose.
• Take with or without food, but consistently at the same time daily for steady effects.
• Pair with non-drug measures like rest or physical therapy for better results.
• Avoid alcohol or sedatives, which amplify drowsiness.
• Track pain levels and report changes to your doctor.

When Not to Use Avoid Calfina CR if:

• Allergic to Tramadol HCl or any excipients (symptoms: rash, itching, swelling, breathing issues).
• Severe respiratory depression or acute asthma.
• Recent use of MAO inhibitors (within 14 days).
• Uncontrolled epilepsy or severe liver/kidney failure.
• History of substance abuse or suicidal thoughts.

Side Effects Common:

• Dizziness, sedation, fatigue, headache.
• Constipation, nausea, vomiting, dry mouth.
• Sweating, indigestion, changes in appetite.

Uncommon / Severe (Stop and seek medical help):

• Seizures, respiratory depression, low blood pressure, collapse.
• Confusion, sleep disturbances, blurred vision, tremors.
• Skin reactions, muscle weakness, hiccups, mood changes (e.g., euphoria).

Precautions & Warnings

• Tell your doctor about other meds like antidepressants, antipsychotics, or pain relievers—may increase drowsiness or seizure risk.
• Use short-term in those prone to abuse; strict supervision needed.
• Tolerance may build, requiring dose adjustments—do not increase without advice.
• Risk of convulsions higher with certain drugs; your doctor will assess suitability.
• May impair driving or machinery—avoid until effects are known.

Drug Interactions

• Carbamazepine (e.g., Tegretol): Speeds up Tramadol breakdown, reducing effectiveness.
• Warfarin (e.g., Coumadin): Increases bleeding risk.
• Heart rhythm drugs, SSRIs/SNRIs, tricyclics, quinidine, phenothiazines, ondansetron: Heighten serotonin syndrome or seizure risk.

Food Interactions

• Can be taken with or without meals; food may ease stomach upset.
• Avoid alcohol—it boosts sedation and breathing risks.
• Grapefruit juice may alter drug levels—limit intake.

Storage/Disposal

• Store at room temperature (15-30°C), away from direct light, heat, and moisture.
• Keep in original packaging, out of reach of children and pets.
• Dispose securely via pharmacy returns; do not flush to avoid environmental harm.

Quick Tips

• Stay hydrated to combat constipation and dry mouth.
• Use a pill organizer for once-daily dosing.
• Report mood shifts or dependency signs early.
• Combine with heat/ice packs for added relief.
• Taper use gradually to ease withdrawal.

Disclaimer This information is provided for educational purposes only and does not replace medical advice. Use only under the supervision of a licensed physician. Do not self-medicate.