Corex-D cough syrup is a standard in Pakistani cold and flu sections, from busy pharmacies in Karachi’s Saddar to Lahore’s Mayo Hospital OPDs, where doctors suggest it for dry coughs and allergy symptoms in respiratory bugs. The mix of dextromethorphan for cough suppression, chlorpheniramine for antihistamine action, ephedrine for decongestion, and sodium citrate for mucus thinning fits PMDC OTC allowances for minor ills, but resistance and misuse concerns keep it scripted for kids or long use. A 120ml bottle from Barrett Hodgson costs PKR 100-150—check Servaid or Dawaai.pk for stock—drawn from cough protocols, not a fever fix without checkup.
Basic Product Details
- Form and Strength: Syrup with dextromethorphan 10mg/5ml, chlorpheniramine maleate 4mg/5ml, ephedrine HCl 8mg/5ml, sodium citrate 100mg/5ml.
- Packaging: 120ml bottle with measuring cap.
- Pricing: PKR 100-150 per bottle, varies by area—generics or equivalents available.
- Brands in Pakistan: Corex-D from Barrett Hodgson, or similar combos like Tussin-DM generics.
Ingredients
- Active: Dextromethorphan HBr, Chlorpheniramine maleate, Ephedrine HCl, Sodium citrate.
- Excipients: Sugar syrup, flavors, preservatives—check for diabetes or allergies.
Drug Class
Antitussive, Antihistamine, Decongestant, Expectorant Combination.
How It Functions
Dextromethorphan calms cough centers in the brain; chlorpheniramine blocks histamine for sneeze/itch relief; ephedrine shrinks nasal vessels for decongestion; sodium citrate thins mucus for easier clearance. In Pakistan’s viral season spikes, it tackles upper respiratory symptoms, but docs warn on ephedrine’s stim effects in heart patients.
Common Applications
Local ENT and GP guidelines target:
- Dry cough and fever in colds.
- Sinus pressure, congestion, runny nose.
- Itchy throat/nose, watery eyes.
- Sneezing from infections, hay fever, allergies.
Dosage Form
Syrup shaken and measured, 5-10ml 3-4 times daily per age/weight.
Potential Side Effects
Common: Drowsiness, nausea, constipation/diarrhea, epigastric distress.
Serious from reports: Cardiac arrhythmia, hypotension, allergic dermatitis, anorexia, vomiting. ER for fast heart or breathing trouble.
Key Warnings and Precautions
PMDC stresses:
- Heart: Ephedrine risks dysrhythmia—avoid in hypertension or arrhythmia.
- Kids: Not under 4; caution under 6—dose strict.
- Pregnancy: Consult—Category C.
- Sedation: No drive if drowsy.
Short-term only (max 7 days); no alcohol.
When It’s Not Suitable (Contraindications)
Skip if:
- Allergic to components.
- On furazolidone, sodium oxybate, or MAOIs last 14 days.
- Severe asthma or prostate issues.
Drug Interactions
Ask doc about:
- MAOIs—hypertensive crisis.
- Sedatives—drowsiness up.
- Beta-blockers—heart effects.
In Case of Overdose
Dizziness, hallucinations, rapid heart—hospital for support.
Missed Dose
Take soon unless near next; skip, no double.
Storage and Disposal
Room temp (15-30°C), tight cap, away from light/heat/kids. Pharmacy disposal expired.
Quick Tips
- Measure accurately.
- Hydrate for mucus thin.
- Stop if symptoms linger >7 days.
Doctor Review
ENT specialists at PIMS or Civil Hospital Karachi use Corex-D for allergic coughs where plain suppressants fail, dosing low in kids amid misuse fears, but switch to nebulizers for wheeze and push flu shots in winter peaks.
Laboratory Screening
If persistent:
- CBC for infection.
- Allergy tests.
This covers Corex-D’s cough relief in Pakistan—symptom aid, doc assesses.
Disclaimer: This is product information only, not a prescription or diagnosis. Consult a qualified Pakistani doctor before using Corex-D cough syrup to ensure it’s safe. Seek immediate care for severe symptoms like rapid heartbeat or confusion.

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